ACE inhibitors / ↑ Risk of severe leukopenia Allopurinol / ↑ Pharmacologic effect of azathioprine R/T ↓ liver breakdown Anticoagulants / ↓ Anticoagulant effect Corticosteroids / With azathioprine, may cause muscle wasting after prolonged therapy Cyclosporine / ↑ Plasma cyclosporine levels Echinacea / Do not give with azathioprine Methotrexate / ↑ Plasma levels of the active metabolite, 6-mercaptopurine Tubocurarine / ↓ Tubocurarine effect and other nondepolarizing neuromuscular blocking agents。
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